Table 2.

outcomes of 12 week randomized placebo controlled crossover trial of oral vitamin B-12 supplement (500 mcg daily) in 43 vegetarians

	Baseline	After Placebo	After Vitamin B-12
Systolic BP (mmHg)	l22±l4	117±13	117±16
Diastolic BP (mmHg)	8l±l2	78±9	79±10
B-l2 (pmol/l)	l34.0±l25.6	185.7±145.4*	379.6±206.2#
Homocysteine (µmol/l)	l6.7±ll.0	13.1±5.0*	11.3±6.0**
Folate (nmol/l)	39.4±l0.4	39.2±14.2	40.0±12.3
LDL-C (mmol/l)	2.5±0.8	2.4±0.7	2.4±0.8
HDL-C (mmol/l)	l.4±0.3	1.4±0.4	1.4±0.3
Glucose (mmol/l)	5.l±0.9	5.1±1.0	5.1±0.6
Reactive Hyperemia (%)	883.9±97.l	900.7±99.9	920.7±75.5
GTN (%)	17.1±2.7	18.2±2.0	18.8±2.1

Compared with baseline

^*P<0.05;

^**p<0.01: #p<0.0001,paired t test. Reactive hyperemia = Velocity-time integral2 × Heart Rate2/Velocity-time integrall × Heart Ratel x100 BP: blood pressure; FMD: brachial flow mediated dilation; GTN: glyceryltrinitrate; HDL-C : high density lipoprotein bound cholesterol; IMT: intima media thickness; LDL-C - low density lipoprotein bound cholesterol