TABLE 3.

In vitro activity of anidulafungin against 315 fluconazole-resistant clinical isolates of Candida spp.^a

Organism	No. tested	Cumulative % susceptible to anidulafungin at:
		0.007 μg/ml	0.015 μg/ml	0.03 μg/ml	0.06 μg/ml	0.12 μg/ml	0.25 μg/ml	0.5 μg/ml	1 μg/ml	2 μg/ml	4 μg/ml	8 μg/ml
C. albicans	41	15	42	66	95	95	95	98	100
C. glabrata	110	1	3	36	81	98	100
C. krusei	146	1	3	40	82	97	99	100
Candida spp.	18	6	17	39	39	39	44	67	83	100
Total	315	3	9	42	81	94	96	98	99	100

^aBroth microdilution testing was done according to CLSI M27-A2 (10), using 24-h incubation and MIC-2 endpoint. Fluconazole resistance is defined as a MIC of ≥64 μg/ml.