Figure 5.
Thin filament structure showing troponin complex, tropomyosin, and actin. TnC, TnI, and the C-terminal portion of TnT bind near Cys190 of tropomyosin. The N-terminal portion of TnT extends along the C-terminal half of tropomyosin. The predicted truncation in ANM would delete a part of the C-terminal end of the TnT molecule that interacts with TnI, TnC, and tropomyosin.