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. 2005 Nov 18;1(3):e24. doi: 10.1371/journal.ppat.0010024

Figure 1. IFN-γ-Mediated Growth Inhibition and Intracellular Killing of T. gondii Are Accompanied by Accumulation of p47 GTPases at the PV.

Figure 1

(A) Astrocytes were induced with the indicated concentrations of IFN-γ and infected with T. gondii 24 h later for 68 h. The growth of intracellular parasites was monitored by uracil incorporation assay. (Inset) Lysates of astrocytes induced with the indicated concentrations of IFN-γ for 24 h were probed for IIGP1 protein by Western blotting.

(B) Untreated or IFN-γ induced astrocytes were infected with T. gondii. After 2 h, extracellular parasites were washed away and cells were either fixed or incubated further for a total of 8 h or 24 h. Shown are the mean values of three independent counts representing a total number of 650–997 cells per time point.