Table 1.
Group and Subject (Sex [Age])a | Ethnicityb | CFTR Mutation Analysisc | CFTR Intron 8 Poly(T) Analysis |
Parents: | |||
1 (M [28]) | White | Negative/ΔF508 | 7T/9T |
2 (F [32]) | White | Negative/ΔF508 | 7T/9T |
3 (F [44]) | White | Negative/ΔF508 | 7T/9T |
4 (M [36]) | AA | Negative/ΔF508 | 9T/9T |
5 (M [54]) | White | Negative/N1303K | 7T/9T |
6 (F [24]) | White | Negative/S549R | 7T/7T |
7 (F [30]) | AA | Negative/3120+1G-A | 7T/7T |
Patients: | |||
1 (F [20]) | White | ΔF508/N1303K | 9T/9T |
2 (F [22]) | White | ΔF508/ΔF508 | 9T/9T |
3 (F [33]) | White | ΔF508/1898+1G-A | 7T/9T |
4 (F [27]) | White | ΔF508/ΔI507 | 7T/9T |
5 (M [28]) | White | ΔF508/ΔF508 | 9T/9T |
6 (F [31]) | White | Negative/ΔF508 | 7T/9T |
7 (M [18]) | White | ΔF508/M1101K | 7T/9T |
8 (M [18]) | White | ΔF508/M1101K | 7T/9T |
Members of the patient group had CF; members of the parent group had offspring with CF who were not necessarily included in the present study.
AA = African American.
Negative = alleles testing negative for the 86 most-common CFTR mutations.