Table 1.
Composition of 126 Multiplex SLE Pedigrees, Separated by Ethnicity
|
Ethnicity(No. [%]) |
||||
| Composition | AfricanAmerican | EuropeanAmerican | Other | Total |
| Total multiplex pedigrees | 40 (31.7) | 77 (61.1) | 9 (7.2) | 126 |
| Total sib pairs (affected and unaffected) | 127 (27.1) | 297 (63.3) | 45 (9.6) | 469 |
| Total nuclear families: | 110 (34.7) | 174 (54.9) | 33 (10.4) | 317 |
| % with 1 or 2 sibs | 71.8 | 69.1 | 75.7 | |
| % with 3–5 sibs | 26.4 | 29.8 | 21.3 | |
| % with >5 sib | 1.8 | 1.1 | 3.0 | |
| Total ARPs: | 52 (29.7) | 112 (64.0) | 11 (6.3) | 175 |
| % total full sibs | 51.9 | 60.7 | 63.6 | |
| % total half sibs | 11.6 | 1.8 | .0 | |
| % total other pairs (avuncular,a grandparental, cousin) | 36.5 | 37.5 | 36.4 | |
a
Niece/aunt, niece/uncle, nephew/aunt, and nephew/uncle pairs.