Table 3.
Results of Models Using One Marker (Single Regression) and Two Markers with Their Interaction (Multiple Regression) for the Concordant and Discordant Sibling Pairs in the Expanded OK Pedigree Collection
|
Parameter Estimates |
|||
| Pedigree Subset and Region | SingleRegression | MultipleRegression | P |
| European American: | |||
| 4p16-15.2 | .2250 | .1577 | .1050 |
| 4q31-33 | .1576 | .0736 | .3020 |
| 4p16-15.2 × 4q31-33 | .1083 | .3150 | |
| 4p16-15.2 | .2250 | .0737 | .3430 |
| 5p15 | .1660 | .0000 | .5910 |
| 4p16-15.2 × 5p15 | .3095 | .0380 | |
| 4q31-33 | .1576 | .1429 | .1140 |
| 5p15 | .1660 | .1541 | .0990 |
| 4q31-33 × 5p15 | .0526 | .4000 | |
| African American: | |||
| 1q22-24 | .3149 | .3008 | .0440 |
| 6p24-23 | .2650 | .2454 | .0780 |
| 1q22-24 × 6p23-22 | .0000 | .6060 | |
| All pedigrees: | |||
| 1q22-24 | .1332 | .1202 | .0320 |
| 6p24-23 | .1309 | .1767 | .0360 |
| 1q22-24 × 6p24-23 | .0000 | .7640 | |
| 1q22-24 | .1332 | .1311 | .0020 |
| 5p15 | .1733 | .1304 | .0002 |
| 1q22-24 × 5p15 | .0000 | .9840 | |
| 6p24-23 | .1309 | .0739 | .2390 |
| 5p15 | .1733 | .1317 | .1050 |
| 6p24-23 × 5p15 | .1770 | .3010 | |