Table 3.

Description of Affection Status and Structure of the 148 Nuclear Families

3A. Description of Affection Status for the Six Phenotypic Groupsa
Affection Status	Large	Strict	Large-Lean	Strict-Lean	Large Young-Onset	Strict Young-Onset
Affected	NIDDM+GI	NIDDM	(NIDDM+GI) with BMI <27	NIDDM with BMI <27	(NIDDM+GI) with age at onset <46	NIDDM with age at onset <46
Unknown	NA	NA+GI	NA+(NIDDM+GI) with BMI >27	NA+GI+(NIDDM with BMI >27)	NA+(NIDDM+GI) with age at onset >46	NA+GI+(NIDDM with age at onset >46)
Nonaffected	NG	NG	NG	NG	NG	NG
3B. No. of Families with n Affected in Each Phenotypic Groupb
n	Large	Strict	Large-Lean	Strict-Lean	Large Young-Onset	Strict Young-Onset
2	43	66	37	40	41	45
3	54	54	19	11	11	6
4	30	18	5	5	3	3
5	12	6	1
6	4	1	3	1
7	4	2
8	1
Total families	148	147	65	57	55	54
Total sib-pairs	677	453	179	113	92	81

^aAffection status was determined taking into account patients' diabetic status (overt diabetes [NIDDM], GI, NG, or data not available [NA]), BMI (kg/m²), and age at diagnosis of diabetes. Three affection statuses were used for the statistical analyses: affected, nonaffected, and unknown (coded 2, 1, and 0, respectively).

^bTotal number of sib pairs was calculated with the following formulae: (number of families with n affected, n = [2–8]) X[nX(n-1)]/2.