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. 2026 Jan 28;27:41. doi: 10.1186/s12859-025-06348-1

Table 2.

Runtime comparisons of modular and combined workflows

Cache1 Analysis1 1 Run 3 Runs 30 Runs
Modular workflow 7 3 10 16 97
Combined workflow 7 3 10 30 300
Improvement 1.9Inline graphic 3.0Inline graphic

1Runtime per dataset

Cache creation is a one-time step in the separated workflow and is repeated for each analysis in the combined workflow

Runtimes are reported in seconds for one or more independent runs, using a reference database of 16,089 compounds and an input sample file containing 89,288 features