Table 2.
a) Genotype prevalence (number and %) for all polymorphisms investigated
| Wildtype | Heterozygous | Homozygous recessive | |
|---|---|---|---|
| 677C>T-MTHFR | 54 (45.8) | 46 (39.0) | 18 (15.3) |
| 1298A>C-MTHFR | 59 (50.0) | 49 (41.5) | 10 (8.5) |
| 80G>A-RFC | 33 (28.0) | 55 (46.6) | 30 (25.4) |
| 2756A>G-MS | 59 (50.0) | 50 (42.4) | 9 (7.6) |
| 66A>G- MSR | 18 (15.3) | 61 (51.7) | 39 (33.1) |
| 19bp deletion DHFR | 36 (30.5) | 58 (49.2) | 24 (20.3) |
| 1561C>T-GCP II | 110 (93.2) | 8 (6.8) | 0 (0) |
| b) Allele number, frequency and carriage of mutant allele for all polymorphisms examined. Carriage implies possession of at least one mutant allele expressed as % of individuals. | |||
| Wildtype allele Allele number | Mutant allele and (frequency) | Carriage of mutant allele (%) | |
|---|---|---|---|
| 677C>T-MTHFR | 154 (0.65) | 82 (0.35) | 54.2 |
| 1298A>C-MTHFR | 167 (0.71) | 69 (0.29) | 50.0 |
| 80G>A-RFC | 121 (0.51) | 115 (0.49) | 72.0 |
| 2756A>G-MS | 168 (0.71) | 68 (0.29) | 50.0 |
| 66A>G- MSR | 97 (0.41) | 139 (0.59) | 84.7 |
| 19bp deletion DHFR | 130 (0.55) | 106 (0.45) | 69.5 |
| 1561C>T-GCP II | 228 (0.66) | 8 (0.34) | 6.8 |