Fig. 1.

Dendritic targeting capacity of the IP₃RI 3′ UTR in cultured hippocampal neurons. (A) Schematic representation of the vectors expressing fusion transcripts of EGFP. The white boxes in the 3′ UTR indicate the positions of the polyadenylation signals (AAUAAA). (B) Ratio of cells showing dendritic localization to total neurons expressing the reporter transcripts (n > 3, total 227-624 neurons per construct). Statistical significance was assessed by using a Student's t test. Values are the mean ± SEM. *, P < 0.05; **, P < 0.01.