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. 2005 Nov 8;102(47):17160–17165. doi: 10.1073/pnas.0508190102

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Copyright © 2005, The National Academy of Sciences

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Fig. 4. — LTD produced by caffeine (10 mM) and nonconjunctive stimulation. (A) LTD was evoked by nonconjunctive stimulation (PC depolarization followed by PF stimulation) in the presence of caffeine (green symbols). LTD was prevented by 1 μM T-588 (red symbols). Data were pooled and normalized to the mean initial PF-EPSC amplitude during the control period before stimulation. (B) Average change in PF EPSC amplitude before (green) and after (red) T-588. Data represent the mean (±SEM). (C) Superimposed sample records of PF-EPSC traces are taken before (red traces) and 30 min after (blue traces) LTD induction in the absence (Upper) and presence (Lower) of T-588.