Table 3. Difference in PF4 and CTAP-III peak intensities between benzene-exposed and unexposed subjects by linear regression.

	Unadjusted* for platelet count		Adjusted† for platelet count
Protein	Regression coefficient	P	Regression coefficient	P
PF4	–0.53	0.0008	–0.54	0.0037
CTAP-III	–1.09	<0.0001	–0.90	<0.0001

^*Linear regression on the natural logarithim (ln) of each protein with exposure status (yes/no) as independent predictor. Analyses are unadjusted, because age, sex, current smoking, recent infections, and alcohol use did not weaken the effect of benzene exposure on any of the identified proteins. Relative difference between exposed and unexposed can be calculated as follows: Exposed/Unexposed = exp^β = exp^(–0.53) = 0.6

^†Linear regression on the ln of each protein adjusted for individual platelet count, which itself was not significant in the model