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| Human IC50, nM
|
BChE selectivity
|
Rat IC50, nM
|
BChE selectivity
|
|||
|---|---|---|---|---|---|---|
| Compound | AChE | BChE | AChE | BChE | ||
| Cymserine | 760 ± 20 | 50 ± 1 | 15-fold | 800 ± 25 | 38 ± 7 | 21-fold |
| PEC | >30,000 | 6 ± 1 | >5,000-fold | >30,000 | 9 ± 2 | >3,300-fold |
| BNC | 110 ± 15 | 1 ± 0.1 | 110-fold | 150 ± 20 | 1 ± 0.5 | 150-fold |
