Table 3.
Unadjusted and adjusted HR for HF hospitalization
| Variables | Unadjusted | Adjusted* | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Age | 1.06 | 1.01–1.11 | 0.019 | |||
| NYHA II-IV | 3.54 | 1.58–7.92 | 0.002 | |||
| Preexisting HF | 4.66 | 2.61–8.33 | <0.001 | |||
| β blocker | 2.17 | 1.14–4.12 | 0.018 | |||
| lg (NT-pro BNP) | 2.02 | 1.53–2.67 | <0.001 | |||
| LAD | 1.11 | 1.06–1.16 | <0.001 | |||
| LVEF | 0.91 | 0.87–0.95 | <0.001 | |||
| PNI | 0.94 | 0.91–0.98 | 0.002 | 0.97 | 0.93–1.01 | 0.142 |
| GNRI | 0.96 | 0.93–0.99 | 0.004 | 0.97 | 0.936–0.997# | 0.032 |
| NPS | 1.53 | 1.13–2.05 | 0.005 | 1.11 | 0.80–1.55 | 0.538 |
| CONUT | 1.20 | 1.01–1.42 | 0.036 | 0.97 | 0.80–1.19 | 0.778 |
| PNI groups | ||||||
| Normal | / | / | ||||
| Mild | 2.23 | 1.16–4.26 | 0.016 | 0.89 | 0.42–1.89 | 0.763 |
| Moderate-to-severe | 6.69 | 1.59–28.15 | 0.010 | 4.66 | 1.03–21.00 | 0.045 |
| GNRI groups | ||||||
| Normal | / | / | ||||
| Mild | 2.48 | 1.18–5.18 | 0.016 | 1.81 | 0.84–3.90 | 0.128 |
| Moderate-to-severe | 2.62 | 0.93–7.39 | 0.069 | 3.02 | 1.02–9.00 | 0.047 |
| NPS groups | ||||||
| Normal | / | / | ||||
| Mild | 0.82 | 0.34–1.97 | 0.650 | 0.59 | 0.24–1.45 | 0.252 |
| Moderate-to-severe | 3.03 | 1.11–8.20 | 0.029 | 1.03 | 0.35–3.03 | 0.962 |
| CONUT groups | ||||||
| Normal | / | / | ||||
| Mild | 1.23 | 0.63–2.38 | 0.542 | 0.82 | 0.41–1.65 | 0.578 |
| Moderate-to-severe | 2.22 | 0.84–5.83 | 0.107 | 0.74 | 0.26–2.10 | 0.569 |
*Pre-existing HF, use of β blocker, lg NT-pro BNP level, LAD, and LVEF were adjusted in the multivariate model. #CI was presented with greater precision due to its proximity to 1.00. Abbreviations: HR, hazard ratio; CI, confidential interval; HF, heart failure; HR, hazard ratio; CI, confidential interval; NYHA, New York Heart Association; lg (NT-pro BNP), the common logarithm of N-terminal pro-brain natriuretic peptide; LAD, left atrium diameter; LVEF, left ventricular ejection fraction; PNI, the Prognostic Nutritional Index; GNRI, the Geriatric Nutritional Risk Index; NPS, the Naples Prognostic Score; CONUT, the Controlling Nutritional Status.