Schematic localization of a unique XLMR syndrome, as implied by the current report, in relation to other reported XLMR conditions in close proximity. Vertical arrows indicate DNA markers tested in the present study. Asterisks (*) indicate markers that have previously been linked to other XLMR conditions. Mutations within the GPC3 gene have been found in SBGS. CS = Cowchock syndrome, GS = Gustavson syndrome, SG = SGBS , XPH = X-linked recessive panhypopituitarism, MR-IGHD = mental retardation with isolated growth hormone deficiency, and MRX = nonspecific XLMR.