Figure 1.

MC1R variation. a, Divergent codons and amino acids, between a chimpanzee sequence and the human consensus sequence, with the codon position indicated (blackened circles). Nucleotides that are different from those of the human consensus sequence are shown in uppercase letters. b, Variant haplotypes. The variants are labeled by a single defining amino acid change compared with the human consensus sequence. Both the codon position (numbers) and variant codons are indicated (blackened circles). Nucleotide that differ from those of the consensus sequence are shown in uppercase letters.