Table 2.
Clinical Characteristics of Patients
|
FS |
Epileptic Seizures |
||||||||||
| Patient Age at |
Patient Age at |
||||||||||
| Subject (Sex, Age[years]) | Status | First Occurrence | Last Occurrence | No. | First Occurrence | Last Occurrence | Pattern | No. | Interictal EEG | Brain Imaging(Technique)a | |
| II-1 (F, 69) | Unknown | … | … | … | 60 years | 60 years | GTCS | 2 | Not available | Not available | |
| II-2 (F, 76) | Unknown | … | … | … | Childhood | 76 years | GTCS | Numerous | Not available | Not available | |
| II-3 (F, 77) | Unknown | … | … | … | 25 years | 30 years | GTCS | 3 | Not available | Not available | |
| III-2 (F, 39) | Present | 9 mo | … | Several | Childhoodb | 32 years | GTCSb | Numerous | Not available | Not available | |
| III-5 (F, 32) | Present | 4 mo | … | Numerous | Childhoodb | 32 years | GTCS,b versive seizures and left hemiclonic seizures | Numerous | Generalized spike-waves, right frontal focus | Normal (CT) | |
| III-6 (F, 48) | Unknown | … | … | … | Childhood | 46 years | GTCS | Several | Slow generalized spikes and waves, photosensitivity | Normal (CT) | |
| III-7 (F, 41) | Present | 3 years | 3 years | 1 | … | … | … | … | … | … | |
| III-8 (M, 45) | Present | 2 years | Unknown | Several | Childhood | 7 years | GTCS | Few | Not available | Not available | |
| IV-1 (F, 19) | Present | 1 year | 3 years | Several | 3 years | 19 years | GTCS absences, absence status, right hemiclonic seizures | Numerous | Generalized spike-waves, 3-Hz generalized discharges | Slight cerebellar atrophyc (MRI) | |
| IV-2 (F, 18) | Present | 9 mo | 4 years | Several | … | … | … | … | … | … | |
| IV-3 (F, 23) | Present | 7 mo | … | Numerous | 7 mo?b | 10 yearsb | GTCSb | Several | Normal | Not available | |
| IV-5 (M, 18) | Present | 1 year | … | Several | Childhoodb | 18 years | GTCS,b myoclonic seizures, atypical absences | Numerous | Slow-background, generalized spike-waves | Small right putaminal ischemic lesion (MRI) | |
| IV-6 (F, 12) | Present | 8 mo | … | Few | Childhoodb | 9 years | GTCSb | Numerous | 3-Hz spike-waves | Normal (CT) | |
| IV-7 (M, 24) | No | … | … | … | 24 years | 24 years | GTCS | 4d | Normal | Normal (CT) | |
a
CT = computed tomography; MRI = magnetic-resonance imaging.
b
No symptom-free interval between FS and epileptic seizures, which were often precipitated by fever.
c
Perhaps caused by chronic phenytoin treatment.
d
One seizure precipitated by sleep deprivation and two seizures precipitated by abrupt cessation of antiepileptic drug.