Table 1.
Mutation Analysis of the CRYGE-Promoter Region in Controls
|
No. of Controls with |
|||||
| Ethnic Group/Haplotype | Haplotype 1a | Haplotype 2b | Haplotype 3c | Haplotype 4d | No. of Alleles |
| Swiss | 23 | 17 | 7 | 1 | 48 |
| Western European | 20 | 14 | 12 | 0 | 46 |
| Eastern European | 3 | 5 | 2 | 0 | 10 |
| Afro-Carribean | 3 | 1 | 4 | 0 | 8 |
| East Indian | 2 | 6 | 0 | 0 | 8 |
| Chinese | 2 | 0 | 4 | 0 | 6 |
| Total | 53 (42.1%) | 43 (34.1%) | 29 (23%) | 1 (.8%) | 126e |
a
tataTa/cCg.
b
tataCa/cCg.
c
tataTa/cTg (proposed Coppock-like–cataract mutation, 5′ to exon 1 [Brakenhoff et al. 1994]).
d
tataCa/cTg.
e
An additional 9 control individuals were sequenced and found to be double heterozygotes.