Table 1.
Two-Point
LOD Score at
θ =a |
||||||
Chromosome2 Marker | .0 | .05 | .1 | .2 | .3 | .4 |
D2S112 | −22.75 | −4.29 | −1.55 | .5 | .94 | .58 |
D2S2313 | −29.31 | −5.94 | −2.75 | −.11 | .62 | .45 |
D2S142 | −7.58 | −1.24 | −.12 | .68 | .79 | .54 |
D2S2330 | −3.53 | 6.79 | 6.87 | 5.92 | 4.32 | 2.25 |
D2S333 | 9.05 | 8.37 | 7.63 | 6.00 | 4.15 | 2.06 |
D2S335 | 4.9 | 4.53 | 4.14 | 3.27 | 2.26 | 1.13 |
D2S1238 | 7.54 | 6.95 | 6.34 | 5.0 | 3.48 | 1.74 |
D2S2314 | 11.73 | 10.87 | 9.96 | 7.92 | 5.58 | 2.88 |
D2S1244 | 10.82 | 10.04 | 9.20 | 7.31 | 5.15 | 2.64 |
D2S1245 | 6.3 | 5.83 | 5.32 | 4.19 | 2.9 | 1.4 |
HOXD13 | 1.38 | 1.17 | .96 | .55 | .24 | .03 |
D2S138 | 11.11 | 10.29 | 9.40 | 4.19 | 2.90 | 1.40 |
D2S364 | −8.79 | 6.19 | 6.33 | 5.50 | 4.04 | 2.11 |
D2S117 | −16.77 | 2.11 | 3.03 | 3.12 | 2.31 | 1.08 |
D2S325 | −19.05 | 1.40 | 2.79 | 3.31 | 2.72 | 1.5 |
Calculated under the assumption of an autosomal-dominant, fully penetrant genetic model (penetrance .99) with a phenocopy rate of .001.