Figure 2.

Three families with linkage to BBS1 (B8, B10 and B19) and three unassigned families (B7, B12, and B15) haplotyped for six polymorphic markers spanning the 26-cM BBS1 interval on chromosome 11q13. Only core pedigrees are presented. Blackened symbols indicate individuals with diagnoses of BBS. Boxed haplotypes (solid and dashed lines) indicate DHs. Double marriage lines depict consanguineous unions, either documented (solid line) or suspected (dashed line). “R” indicates that the DH is recombinant.