Table 3.
LD at the BBS1 Locus on Chromosome 11q13 among Five Newfoundland Kindreds[Note]
|
DH for Kindred |
Normal Haplotype
for Kindred |
|||||||||||||||||||
| B8 |
B10 |
B12 |
B15 |
B19 |
B8 |
B10 |
B12 |
B15 |
B19 |
|||||||||||
| Locus | p | m | p | m | p | m | p | m | p | m | p | m | p | m | p | m | p | m | p | m |
| 1298 | 10 | 10 | 7 | 10 | 7 | 9 | 11 | 11 | … | … | 5 | 7 | 10 | 7 | 4 | 7 | 8 | 13 | … | … |
| 956 | 8 | 8 | 10 | 8 | 7 | 5 | 7 | 7 | 11 | 11 | 10 | 3 | 11 | 7 | 1 | 2 | 5 | 6 | 11 | 7 |
| 480 | 6 |
6 |
9 | 6 |
5 |
9 |
5 |
5 |
9 |
9 |
9 | 5 |
5 |
5 | 6 |
5 |
8 | 5 |
4 |
5 |
| 4205 | 4 | 4 | 3 |
4 | 4 | 4 | 4 | 4 | 4 |
4 |
3 | 4 |
4 |
5 | 4 |
4 | 3 | 4 |
4 | 4 |
| 1883 | 10 | 10 | 10 | 10 | 10 | 8a | 10 | 10 | 7 |
7 |
9 |
12 |
12 |
9 |
13 |
10 |
12 | 11 | 10 | 7 |
| 4945 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 |
4 | 10 | 10 |
9 | 9 |
| PYGM | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 |
8 | 6a | 8 |
2 | 4 | 4 | 8 | 8 |
4 |
| 4946 | 5 |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
4 | 5 |
5 |
4 | 4 | 1 | 1 | 5 |
3 | 3 |
| 4940 | 5 | 5 | 7 | 5 | 7 | 5 | 7 | 7 | 3 | 3 | 5 | 5 | 5 | 5 | 5 | 3 | 5 | 7 | 7 | 5 |
| 4938 | 5 | 5 | 3 | 5 | 5 | 3 | 5 | 5 | 5 | 5 | 9 | 3 | 5 | 3 | 5 | 9 | 5 | 5 | … | 9 |
| 449 | 7 | 7 | 3 | 7 | 3 | 6 | 5 | 5 | 3 | 3 | 5 | 3 | 4 | 3 | 4 | 2 | 5 | 5 | 3 | 4 |
| 4941 | 9 | 9 | 11 | 9 | 2 | 2 | 4 | 4 | 4 | 4 | 8 | 3 | 6 | 11 | 2 | 4 | 4 | 6 | 4 | 4 |
| 913 | 7 | 7 | 6 | 7 | 6 | 5 | 6 | 6 | 6 | 6 | 7 | 6 | 5 | 5 | 5 | 7 | 6 | 6 | 7 | 6 |
| FGF3 | 5 | 5 | 7 | 5 | 9 | 9 | 9 | 9 | … | … | 4 | 5 | 5 | 9 | 5 | 5 | 12 | 5 | … | … |
Note.— Haplotypes are arranged with paternal haplotype (p) on the left and the maternal haplotype (m) on the right. Specific alleles associated with disease chromosomes are boxed.
a
Allele is not associated with disease chromosome.