Table 3. IC50 value for the most potent cytotoxic compound's inhibition of VEGFR-2 kinase (4e).
| Compound | IC50 ± SDa (μM) |
|---|---|
| VEGFR-2 | |
| 4e | 0.618 ± 0.04 |
| Sorafenib | 0.560 ± 0.01 |
The values are the average of three separate tests. A sigmoidal non-linear regression analysis of % inhibition across five distinct concentrations of each chemical was used to calculate the IC50 values.