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. 2026 Jan 22. Online ahead of print. doi: 10.1039/d5md00980d

Table 3. IC50 value for the most potent cytotoxic compound's inhibition of VEGFR-2 kinase (4e).

Compound IC50 ± SDa (μM)
VEGFR-2
4e 0.618 ± 0.04
Sorafenib 0.560 ± 0.01
a

The values are the average of three separate tests. A sigmoidal non-linear regression analysis of % inhibition across five distinct concentrations of each chemical was used to calculate the IC50 values.