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. 2000 Oct 5;67(5):1154–1162. doi: 10.1016/s0002-9297(07)62946-2

Table 2.

Results of Genomewide Screen[Note]

P fora
Chromosome and Locus Distance from pter(cM) LR χ2 TDT Allele(bp) TR:NT Phenotype
1:
 D1S468 4 .0002 NS Strict asthma
 D1S1597 30 .0008 NS Loose asthma
 D1S3669 37 .0005 NS Strict asthma
 D1S239b 139 NS .0005 242 52:22 +SPT cockroach
2:
 D2S2944 210 NS 4 × 10−5 115 57:21 +SPT cockroach
.0009 NS +SPT HDM
3:
 D3S3564b 68 .0004 NS Loose asthma
 D3S2459 119 .0007 NS +SPT mold
5:
 D5S1470 45 .0010 .0061 177 25:9 BHR
 D5S1462 105 .0007 .028 193 24:11 Loose asthma
 D5S1453b 115 .0010 NS Symptoms
 D5S2014b 153 .0009 NS Symptoms
8:
 D8S1477 60 .0004 NS Strict asthma
 D8S1110 67 .0006 NS Strict asthma
 D8S1136 82 .0009 .039 257 14:5 Strict asthma
 D8S2324 94 .0007 NS +SPT
9:
 D9S938 111 NS .0005 409 44:17 Symptoms
11:
 D11S899b 23 .0003 NS +SPT mold
13:
 D13S787b 9 .0006 NS Symptoms
14:
 gata193a07 96 .019 .0001 343 51:19 Loose asthma
16:
 D16S539 125 .0008 .029 152 78:53 +SPT mold
18:
 ADYCYAP1 0.6 .0002 NS Symptoms
19:
D19S900b 67 .0010 .0072 165 41:20 BHR
 D19S540b 70 .0004 NS BHR
20:
 D20S470 39 NS .001 298 16:2 +SPT HDM

Note.— All loci with P⩽.001 by either the LR χ2 test or the TDT are shown for phenotypes with the most significant P value at that locus (for definitions of phenotypes see Subjects and Methods). Six loci showing some evidence for linkage by both tests are shown in boldface.

a

NS = not significant (P⩾.05).

b

Region (defined by 20 cM) identified in earlier studies (Ober et al. 1998, 1999).