Table 2.
P
fora |
||||||
Chromosome and Locus | Distance from pter(cM) | LR χ2 | TDT | Allele(bp) | TR:NT | Phenotype |
1: | ||||||
D1S468 | 4 | .0002 | NS | … | … | Strict asthma |
D1S1597 | 30 | .0008 | NS | … | … | Loose asthma |
D1S3669 | 37 | .0005 | NS | … | … | Strict asthma |
D1S239b | 139 | NS | .0005 | 242 | 52:22 | +SPT cockroach |
2: | ||||||
D2S2944 | 210 | NS | 4 × 10−5 | 115 | 57:21 | +SPT cockroach |
.0009 | NS | … | … | +SPT HDM | ||
3: | ||||||
D3S3564b | 68 | .0004 | NS | … | … | Loose asthma |
D3S2459 | 119 | .0007 | NS | … | … | +SPT mold |
5: | ||||||
D5S1470 | 45 | .0010 | .0061 | 177 | 25:9 | BHR |
D5S1462 | 105 | .0007 | .028 | 193 | 24:11 | Loose asthma |
D5S1453b | 115 | .0010 | NS | … | … | Symptoms |
D5S2014b | 153 | .0009 | NS | … | … | Symptoms |
8: | ||||||
D8S1477 | 60 | .0004 | NS | … | … | Strict asthma |
D8S1110 | 67 | .0006 | NS | … | … | Strict asthma |
D8S1136 | 82 | .0009 | .039 | 257 | 14:5 | Strict asthma |
D8S2324 | 94 | .0007 | NS | … | … | +SPT |
9: | ||||||
D9S938 | 111 | NS | .0005 | 409 | 44:17 | Symptoms |
11: | ||||||
D11S899b | 23 | .0003 | NS | … | … | +SPT mold |
13: | ||||||
D13S787b | 9 | .0006 | NS | … | … | Symptoms |
14: | ||||||
gata193a07 | 96 | .019 | .0001 | 343 | 51:19 | Loose asthma |
16: | ||||||
D16S539 | 125 | .0008 | .029 | 152 | 78:53 | +SPT mold |
18: | ||||||
ADYCYAP1 | 0.6 | .0002 | NS | … | … | Symptoms |
19: | ||||||
D19S900b | 67 | .0010 | .0072 | 165 | 41:20 | BHR |
D19S540b | 70 | .0004 | NS | … | … | BHR |
20: | ||||||
D20S470 | 39 | NS | .001 | 298 | 16:2 | +SPT HDM |
Note.— All loci with P⩽.001 by either the LR χ2 test or the TDT are shown for phenotypes with the most significant P value at that locus (for definitions of phenotypes see Subjects and Methods). Six loci showing some evidence for linkage by both tests are shown in boldface.
NS = not significant (P⩾.05).