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. 2005 Nov 23;115(12):3613–3622. doi: 10.1172/JCI25342

Figure 9.

Figure 9

Differential urinary levels of TFF1 in CaOx stone formers compared with normal healthy controls. (A) Urinary TFF1 concentrations were measured with ELISA using equal amounts (40 μg) of the total anionic proteins isolated from 10 ml urine of each donor. Urinary concentrations of TFF1 in patients with idiopathic CaOx kidney stone (2.66 ± 0.46 ng/ml; n = 23, 12 males and 11 females) were significantly lower than those in normal healthy individuals (6.67 ± 0.93 ng/ml; n = 30, 14 males and 16 females). (B) After normalization with urine Cr, the relative amounts of TFF1 in the urine of CaOx stone patients remained significantly less (3.24 ± 0.62 versus 17.19 ± 3.49 ng/mg Cr). (C) This difference remained highly significant after normalization with total protein (11.08 ± 3.21 versus 247.27 ± 53.68 ng/mg total protein). *P < 0.0001.