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. 2005 Apr;125(4):377–394. doi: 10.1085/jgp.200409228

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Copyright © 2005, The Rockefeller University Press

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Figure 11. — Kinetic analysis of the spontaneous openings in the absence of ATP. (A) A representative ΔR/E1371S-CFTR current trace from an excised inside-out patch exposed to ATP-free solution for several minutes before 1 mM ATP was applied. (B) Similar experiment as described in A, but with ΔR-CFTR channels. The open times of these spontaneous openings from several patches containing ΔR/E1371S-CFTR (C) or ΔR-CFTR (D) were pooled together to construct survivor plots.