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. 2005 Apr;125(4):377–394. doi: 10.1085/jgp.200409228

Figure 3.

Figure 3.

Macroscopic current relaxation for ΔR/E1371S-CFTR opened with 10 μM ATP. ΔR/E1371S-CFTR channels were activated with 10 μM ATP until the current reached a steady state. Then the nucleotide was washed out. (A) Sample trace. (B) Ensemble currents were generated by pooling data from 22 experiments. The insets show the first two components of the current relaxation. The dash line represents current relaxation of ΔR/E1371S-CFTR upon removal of 1 mM ATP (from Fig. 2 B).