Experimental paradigm comprising separate-day, randomly ordered, fasting iv infusions of saline (A), l-arginine/GHRH (in tandem) (B), l-arginine/GHRP-2 (in tandem) (C), and constant combined GHRH/GHRP-2 (D) in healthy young adults. A maximally effective dose of each secretagogue was used to “clamp” correspondingly paired receptor-effector pathways (Subjects and Methods).