Table 3.
Effect of Ras transfection on transepithelial electrical parameters
| Potential difference | Resistance | Short circuit current | |
|---|---|---|---|
| pBabe | 1.2 ± 0.1 | 161 ± 6 | 7.3 ± 0.3 |
| Ras | 0.5 ± 0.1a | 229 ± 19c | 2.1 ± 0.1a |
| Ras-A | 0.3 ± 0.1a,b | 342 ± 32c,d | 1.0 ± 0.1a,e |
Data represent the mean ± SE of n = 7 cell sheets. Potential difference is given in millivolts, resistance is given in ohms × square centimeter, and short circuit current is given in microamps per square centimeter. All potential differences were lumen negative.
p < 0.001 relative to pBabe.
p < 0.02 relative to Ras.
p < 0.01 relative to pBabe.
p < 0.01 relative to Ras.
p < 0.002 relative to Ras.