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Synthetic lethal interactions between erg3Δ and mutations that impair membrane traffic
| Functions | Mutation |
|---|---|
| Viable | |
| Retrograde transport from late endosomes | vps5Δ, vps17Δ, vps26Δ, vps29Δ |
| Endocytic internalization | las17-11, arp2-1 |
| Late stages of exocytosis | sec2-56, sec4-2 |
| Inviable | |
| Endocytic recycling | vps51Δ, vps52Δ, vps54Δ, ypt6Δ, rcy1Δ |
Viability of the double mutant was inferred from the growth phenotype of the tetrad segregants.
