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Anti-TNF therapy in ankylosing spondylitis – open questions
| Long-term efficacy? |
| Arrest of progression of ankylosis? |
| Differing responses in different targets? |
| Dosage? |
| Intervals? |
| Continous or intermittent therapy? |
| Individualization of treatment? |
| Long-term safety? |
| Repeated screening for autoantibodies? |
| Adding of DMARDs to suppress antibody formation? |
| Duration of tuberculosis prophylaxis? |
