Table 1.
Cohort characteristics
| CON | MCI-Aβ+ | AD | DLB | FTD | ||
|---|---|---|---|---|---|---|
| N | 55 | 39 | 47 | 54 | 50 | |
| Sex (%) | F | 20 (36.4) | 18 (46.2) | 31 (66.0) | 9 (16.7) | 16 (32.0) |
| M | 35 (63.6) | 21 (53.8) | 16 (34.0) | 45 (83.3) | 34 (68.0) | |
| Age (years) | 57 (54–61)a, b,c, d | 68 (65–71)d, e | 65 (62–68)c, e | 69 (66–73)b, d,e | 64 (59–69)a, c,e | |
| MMSE scores | 29 (28–30)a, b,c, d | 26 (24–27)b, c,e | 21 (19–23)a, c,d, e | 24 (21–26)a, b,e | 25 (24–27)b, e | |
| Positive CSF AD profile, n (%) | 0 (0.0) | 35 (92.1) | 47 (100.0) | 12 (24.5) | 4 (8.3) | |
Continuous data is represented as median ± interquartile range and dichotomous data as the number of cases with a percentage of the total (%)
Differences between groups were determined using the Kruskal Wallis test with Bonferroni correction
Abbreviations: CON controls, AD Alzheimer’s disease, CSF cerebrospinal fluid, MCI-Aβ+ mild cognitive impairment with amyoid pathology, DLB dementia with Lewy bodies, FTD Frontotemporal dementia, MMSE mini-mental state examination
b p < 0.05 compared to AD
c p < 0.05 compared to DLB
d p < 0.05 compared to FTD
e p < 0.05 compared to Controls