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. 2026 Jan 27;23:27. doi: 10.1186/s12986-025-01061-5

Table 3.

Meta-regression between changes in glycemic indices and administered doses and intervention duration of melatonin

Regression Dose-Response
Dose (mg/d) Duration (week) Dose (mg/d) Duration (week)
Variables Coefficient p-value Coefficient p-value Coefficient p-value Coefficient p-value
FBS (mg/dl) −0.02 0.851 0.12 0.540 24.90 0.648 −2.60 0.641
Insulin (µIU/ml) −0.58 0.034 0.13 0.697 618.37 0.001 11.06 < 0.001
HbA1c (%) −0.82 0.786 13.09 0.314 5.94 0.503 0.52 0.338
HOMA-IR −1.40 0.120 1.80 0.492 0.03 0.003 0.96 0.304