Table 2.

Comparison of renal function between two groups of patients before and after treatment

Parameter	Time	CM group (n = 107)	CSCT group (n = 104)	t	P value
Serum creatinine (mg/dL)	Baseline	1.04 ± 0.32	1.04 ± 0.29	0.122	0.903
	6 months	1.05 ± 0.35	1.06 ± 0.31	0.265	0.791
GFR (mL/minute/1.73 m2)	Baseline	50.83 ± 5.01	50.92 ± 5.19	0.126	0.900
	6 months	50.13 ± 4.61	50.52 ± 4.87	0.603	0.547
ACR (mg/g)	Baseline	211.51 ± 30.11	207.54 ± 30.15	0.956	0.340
	6 months	158.11 ± 28.85	145.87 ± 29.23	3.062	0.002

GFR: Glomerular filtration rate; ACR: Albumin/creatinine ratio; CM: Canagliflozin monotherapy; CSCT: Canagliflozin and semaglutide combination therapy.