| MASLD | Metabolic dysfunction-associated liver disease |
| MASH | Metabolic dysfunction-associated steatohepatitis |
| HCC | hepatocellular carcinoma |
| PNPLA3 | patatin-like phospholipase domain-containing 3 |
| LDs | lipid droplets |
| ROS | oxidative reactive species |
| mt-ccf | mitochondrial DNA fragments |
| HEPs | hepatocytes |
| PZ | Portal zone |
| CZ | Central zone |
| NPCs | non-parenchymal cells |
| WT | wild-type |
| T2DM | Type 2 Diabetes Mellitus |
| H&E | Hematoxylin-Eosin |
| BMI | body mass index |
| ALT | alanine aminotransferase |
| UMI | Unique Molecular Identifiers |
| HSCs | hepatic stellate cells |
| GO | Gene Ontology |
| TCA | citrate cycle |
| NAS | NAFLD Activity Score |
| TM6SF2 | transmembrane 6 superfamily member 2 |
| MBOAT7-TMC4 | Membranebound O-acyltransferase domain containing 7-transmembrane channel-like 4 |
| HPCs | hepatic progenitor cells |
| HpSC | hepatic stem cells/progenitor cell |