Table 1.

Genomic test results by next generation sequencing.

Detected gene	Alterations	Alteration type	VAF or CN
TP53	NM_000546.6:c.1024C>T,p.R324*	Nonsense mutation	43.79%
TP53	NM_000546.6:c.743G>A,p.R248Q	Missense mutation	41.07%
BARD1	NM_000465.4:c.513del,p.D172Mfs*40	Frameshift deletion	20.98%
ATR	NM_001184.4:c.2320dup4,p.I774Nfs*3	Frameshift insertion	8.85%
MSH2	NM_000251.3:c.942 + 3A>T	Splice site mutation	46.03%
MSH6	NM_000179.3:c.3261dup,p.F1088Lfs*5	Frameshift insertion	14.07%
PDGFRA	amplification	Copy number gain	13.82

VAF, variant allele frequency; CN, copy number; NGS, next-generation sequencing;”*” indicates a stop codon.