Table 2.
Summary of the immunohistochemistry (IHC) profile.
| Marker | Expression | Significance |
|---|---|---|
| S-100 | Strongly positive (Strongly +) | Characteristic marker for Schwannian differentiation |
| Vimentin (Vim) | Positive (+) | Consistent with mesenchymal origin |
| INI-1 | Positive (+) | INI-1 protein expression is retained |
| Ki-67 | Low (\sim1–2%) | Indicates low proliferative activity (consistent with benignity) |
| CD34 | Focally positive (focally +) | Contributes to differential diagnosis (e.g., neurofibroma, spindle cell lipoma) |
| β-catenin | Negative (−) | Rules out aggressive fibromatosis |
| SMA | Negative (−) | Rules out myofibroblastic differentiation |
| Desmin | Negative (−) | Rules out myogenic tumors |
| CD31, EMA, MUC4, SS18-SSX, STAT6 | All negative (−) | Excludes specific sarcoma subtypes and mimics |