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. 2026 Jan 30;13:1645343. doi: 10.3389/fchem.2025.1645343

TABLE 2.

Amino acid residues of D-pathway, located sterically equivalent sites.

Bovine R. sphaeroides P. denitrificans T.thermophilus P. stutzeri
Y19 Y33 Y35 F24 F17
M71 I112 I104 Q82 G70
N80 N121 N113 V80 Y78
D91 D132 D124 R100 L89
N98 N139 N131 M106 A95
N163 N207 N199 I162 V144
G239 G283 G275 G232 G206
E242 E286 E278 I235 A209
H291 H334 H326 H283 H258
T316 T359 T351 S309 S283
K319 K362 K354 T312 G286

The D-pathways of T. thermoplilus and P. stutzeri CcOs are inactive.