Fig. 13.

miR-20b-5p inhibition restores the balance of ferroptosis-related proteins following circDNMT3B knockdown. Representative Western blots and quantitative data demonstrating that inhibition of miR-20b-5p upregulates SLC7A11 and GPX4 protein levels while downregulating ACSL4 and COX-2 in pancreatic tissue of the indicated groups. A Expression level of ACSL4 protein in pancreatic tissue; B Expression level of COX-2 protein in pancreatic tissue; C Expression level of SLC7A11 protein in pancreatic tissue; Expression level of GPX4 protein in pancreatic tissue.Data are mean ± SD (n = 6). ^nsP > 0. 05,*P < 0.05 vs. shRNA-circDNMT3B + MIRi-NC + SAP + Homo group