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. 2026 Feb 12;26:120. doi: 10.1186/s12876-025-04600-9

Table 1.

Histopathological scoring criteria for pancreatic injury

Score Edema Acinar Necrosis Inflammatory Infiltration
0 Absent Absent 0–5 white blood cells (WBCs) per high-power field (HPF)
1 Diffuse expansion of lobular septa 1–4 necrotic cells per HPF 6–15 WBCs per HPF
2 Diffuse and extensive expansion of interlobular spaces 5–10 necrotic cells per HPF 16–25 WBCs per HPF
3 Diffuse expansion of acinar septa 11–16 necrotic cells per HPF 26–35 WBCs per HPF
4 Diffuse expansion of intercellular spaces > 16 necrotic cells per HPF Extensive necrosis with confluence > 35 WBCs per HPF, or confluent microabscesses

The degree of acinar cell necrosis and inflammatory infiltration was calculated as the average of every 10 fields of view under high-power field (HPF, ×200)