Figure 4. The frequency of vRNA+ cells in the colon is correlated with the frequency of vRNA+ cells in blood.
(A) Scatter plot of frequency of vRNA+ cells in blood cells vs. vRNA+ cells in colon-derived T cells for all conditions (left), unstimulated cells (middle), and stimulated cells (right). Spearman’s correlation coefficients and P values are shown. Each data point represents a single participant. (B) Scatter plots of the frequency of vRNA+ cells in blood cells (left) or colon-derived T cells (right) vs. infectious units per million cells (IUPM) calculated from a quantitative viral outgrowth assay (QVOA) of blood CD4+ T cells for each PWH. Spearman’s correlation coefficients and P values are shown. Each data point represents a single participant.
