Fig. 7. The eye ablation phenotype caused by ectopic expression of Jafrac2 is contingent on DIAP1 binding and is suppressed by co-expression of DIAP1 and p35. The eye phenotypes of GMR-akp-jafrac2/+, GMR-ava-rpr/+ and GMR-akp-rpr/+ transgenic flies on their own (A, F and K), or in combination with th⁴ (B, G and L), GMR-diap1 (C, H and M), GMR-p35 (D, I and N) or Df(3L)AC1 [indicated as Df(Dronc); E, J and O] are shown. The th⁴ diap1 mutation suppresses AKP-Jafrac2 but enhances AVA- and AKP-Rpr induced eye phenotypes. Co-expression of DIAP1 and p35 rescues cell death induced by Jafrac2 and Rpr. Flies with a chromosomal deletion that removes the dronc locus (Df(3L)AC1) display a suppressed Jafrac2 and Rpr eye phenotype.