Table 1.
Quantitative Coronary Plaque Analysis and Physiological Assessment at Baseline and After 8 Months of Intensive Lipid-Lowering Therapy
| Baseline |
8-Month Follow-Up |
Change |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vessel Volume, mm3 | Lumen Volume, mm3 | Plaque Volume (Fibrous/Fibrous Fatty/NC/Calcium), mm3 | PAV | Lipidic Volume (Fibrous Fatty/NC), mm3 | FFRCT | Vessel Volume, mm3 | Lumen Volume, mm3 | Plaque Volume (Fibrous/Fibrous Fatty/NC/Calcium), mm3 | PAV | Lipidic Volume (Fibrous Fatty/NC), mm3 | FFRCT | TPV, mm3 | PAV | Lipidic Volume, mm3 | ΔFFRCT | |
| Total | 1940 | 1,412 | 526 (339/108/39/40) | 32% | 147 (108/39) | n/a | 2,213 | 1783 | 428 (342/3/1/81) | 19% | 4 (3/1) | n/a | −98 (–19%) | −8% | −143 (–97%) | n/a |
| LAD | 972 | 658 | 312 (200/55/25/32) | 25% | 80 (55/25) | 0.83 | 990 | 778 | 210 (156/2/0/52) | 21% | 2 (2/0) | 0.88 | −101 (−33%) | −11% | −78 (–98%) | +0.05 |
| LCx | 341 | 256 | 85 (54/17/6/7) | 21% | 23 (17/6) | 0.74 | 395 | 335 | 59 (42/0/0/17) | 15% | 0 (0/0) | 0.93 | −26 (−31%) | −10% | −23 (–100%) | +0.19 |
| RCA | 627 | 498 | 129 (85/36/8/0) | 27% | 44 (36/8) | 0.92 | 828 | 670 | 158 (143/2/1/12) | 19% | 3 (2/1) | 0.94 | +29 (+22%) | −1% | −42 (–95%) | +0.02 |
FFRCT = CT-derived fractional flow reserve; LAD = left anterior descending artery; LCx = left circumflex artery; n/a = not applicable; NC = necrotic core; PAV = percentage atheroma volume; RCA = right coronary artery; TPV = total plaque volume.