Table 1.
Mutation | Origin | S | L | J | IA | G | SA | K | B | UAE | O | E | T | A |
IVSI-110 (G > A) | East Med | 24 | 33 | 22 | 26.4 | 37.5 | 22 | — | 1.5 | 1.7 | 0.5 | 33 | 12.3 | 24.7 |
IVSI-1 (G > A) | Med | 17 | 15 | 6.6 | 8 | 20 | 7 | 7.3 | 3 | — | 1 | 11.3 | 0.9 | 11.7 |
Cd5 (−CT) | Med | 8.5 | 4 | 3.3 | 0.64 | 10 | — | — | — | 4 | 0.5 | 2.4 | 1.8 | — |
−30 (T > A) | Turkish | 7 | 0.5 | — | 0.64 | — | — | — | — | — | — | — | 2.6 | 0.4 |
Cd39 (C > T) | West Med | 6.4 | 0.5 | 2 | 8 | 11.5 | 20 | 7.3 | 24.2 | 5 | 1 | 1.5 | 27 | 27.6 |
IVSI-6 (T > C) | West Med | 4 | 15 | 6.6 | 14.7 | 7.5 | 7 | 7.3 | — | 3.5 | — | 13.6 | 6 | 3.3 |
IVSII-1 (G > A) | Med | 4 | 10 | 19.8 | 7 | 1 | 15 | 29 | 6.1 | 3.3 | 3.5 | 3 | — | — |
Cd15 (G > A) | Asian-Ind | 3.5 | — | — | 0.64 | — | — | — | 1.5 | 1.5 | 0.5 | — | — | — |
−88 (C > T) | Asian-Ind | 2 | 1.5 | — | — | — | — | — | — | — | — | — | — | — |
−87 (C > G) | Med | 2 | 1.5 | 2 | — | — | — | — | — | — | — | 1.2 | — | — |
IVSI-116 (T > G) | Med | 1.4 | — | — | — | — | — | — | — | — | — | — | — | — |
IVSII-745 (C > G) | Med | 1.4 | 1 | 12 | 6 | — | — | — | — | — | — | 5.6 | 4.4 | 0.9 |
Cd8/9 (+G) | Asian-Ind | 1.4 | 0.5 | — | — | — | 2.5 | 1.3 | 1.5 | 7 | — | 0.3 | — | — |
Cd37 (G > A) | Saud, Egypt | 1.4 | — | 8.8 | 7.4 | 1 | — | — | — | 1 | — | 0.6 | — | — |
Cd8 (−AA) | Turkish | 0.7 | 2.5 | — | 6 | — | 10 | 3 | — | 4 | — | 1.8 | 0.9 | — |
25 bp deletion | Asian-Ind | 0.7 | 1 | — | — | — | 14 | 7.3 | 36 | 8 | 5.5 | — | — | — |
Cd29 (C > T) | Lebanese | — | 7 | — | — | — | — | — | — | — | — | — | — | — |
Cd30 (G > C) | UAE | — | 3 | — | — | — | — | — | — | 3 | — | — | — | — |
290 bp deletion | Turk, Iran | — | 2 | — | — | — | — | — | — | — | — | — | — | — |
Cd44 (−C) | Kurdish | — | 1 | — | — | — | 7.5 | 1 | 4.5 | 1.3 | 9.6 | — | 4.4 | — |
IVSI-5 (G > C) | Asian-Ind | — | 0.5 | 5.5 | 2.6 | — | 10 | 18.8 | 16.7 | 55 | 61.6 | — | — | 0.4 |
Cd27 (G > T) | Med | — | — | 3.3 | — | 1 | — | — | — | — | — | 0.3 | 0.9 | 0.4 |
IVSII-848 (C > A) | Egyptian | — | — | 2 | — | — | — | — | — | 0.5 | — | 8.6 | 0.9 | 0.4 |
Cd6 (−A) | Med | — | — | 1 | — | 5 | 7 | — | — | — | — | 1 | 10.5 | 17 |
IVSII-3' (C > A) | Black | — | — | — | 0.32 | — | — | — | — | — | — | — | — | — |
AATAAA > A | Arab | — | — | — | — | 2.5 | — | — | — | — | — | — | — | — |
IVSI-5 (G > T) | Med | — | — | — | — | — | 2 | — | — | — | — | — | — | — |
Cap + 1 (A > C) | Asian-Ind | — | — | — | — | — | 1 | — | — | — | — | 0.6 | — | — |
Cd36/37 (−T) | Kurd, Iran | — | — | — | — | — | 11.5 | — | — | 0.4 | 1 | — | — | — |
−88 (C > A) | Kurdish | — | — | — | — | — | — | — | 1.5 | — | — | 0.6 | — | — |
Cd35 (−C) | Indonesian | — | — | — | — | — | — | — | 1.5 | — | — | — | — | — |
Cd35 (−C) | Indonesian | — | — | — | — | — | — | — | 1.5 | — | — | — | — | — |
Cd41/42 (−TCTT) | Asian-Ind | — | — | — | — | — | — | — | 1.5 | — | — | — | — | — |
Cd82/83 (−G) | Azerbaijian | — | — | — | — | — | — | — | — | 1 | — | — | — | — |
Cd37 (−G) | Kurdish | — | — | — | — | — | — | — | — | 1 | 0.5 | — | — | — |
AATAAA > AATAAG | Kurdish | — | — | — | — | — | — | — | — | 0.8 | — | — | — | — |
Cd110 (T > C) | Japanese | — | — | — | — | — | — | — | — | 0.8 | — | — | — | — |
−101 (C > T) | Turkish | — | — | — | — | — | — | — | — | 0.8 | — | — | — | — |
Cd30 (AGG > AGC) | various | — | — | — | — | — | — | — | — | 0.4 | — | — | — | — |
Cd30 (G > A) | Bulgarian | — | — | — | — | — | — | — | — | — | 0.5 | — | 2.6 | 0.9 |
Hb Dofar | Omani | — | — | — | — | — | — | — | — | — | 6.6 | — | — | — |
619 bp deletion | Indian | — | — | — | — | — | — | — | — | — | 4 | — | — | — |
HbE | Asian-Ind | — | — | — | — | — | — | — | — | — | 0.5 | — | — | — |
Cd29 (−G) | Japanese | — | — | — | — | — | — | — | — | — | — | 1.2 | — | — |
Cd106/107 (+G) | Black | — | — | — | — | — | — | — | — | — | — | 0.6 | — | — |
Cd28 (−C) | Egypt | — | — | — | — | — | — | — | — | — | — | 0.3 | — | — |
Cd25/26 (+T) | Tunisian | — | — | — | — | — | — | — | — | — | — | — | 0.9 | — |
IVSI-2 (T > A) | Algerian | — | — | — | — | — | — | — | — | — | — | — | 0.9 | 1.3 |
IVSI-5 (G > A) | Algerian | — | — | — | — | — | — | — | — | — | — | — | 0.9 | 0.9 |
−29 (A > C) | Black | — | — | — | — | — | — | — | — | — | — | — | — | 3.8 |
IVSI-2 (T > C) | Black | — | — | — | — | — | — | — | — | — | — | — | — | 3.3 |
IVSII-843 (T > G) | Algerian | — | — | — | — | — | — | — | — | — | — | — | — | 0.4 |
Total mutations | 16 | 18 | 13 | 13 | 10 | 14 | 9 | 12 | 21 | 15 | 19 | 16 | 16 | |