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. 2026 Feb 12;14:e20686. doi: 10.7717/peerj.20686

Figure 3. Diagnostic modeling and external validation.

Figure 3

(A) ROC curves of GLM, LASSO, RF, and XGB classifiers in the training set (TCGA). (B) Bootstrap-validated AUC distribution for each model. (C) SHAP values showing probe importance in the diagnostic model. (D) External validation performance of GLM and XGB models in validated set (GSE121849).