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. 2026 Feb 12;14:e20686. doi: 10.7717/peerj.20686

Figure 7. Single-cell landscape of SLC7A11 and crosstalk of SLC7A11 and immune checkpoints in LUSC.

Figure 7

(A) UMAP project of major cell types in single-cell RNA-seq data. (B) Distribution of SLC7A11 expression across cell clusters. (C) Pathways enriched in epithelial cells with high SLC7A11 expression. (C) Pathways enriched in epithelial cells with low SLC7A11 expression. (E) PPI network of SLC7A11 and related immune-checkpoint molecules. (F) Heatmap of co-expression between SLC7A11 and immune-checkpoint genes. *** P < 0.001.