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. 2026 Jan 2;10(1):103333. doi: 10.1016/j.rpth.2025.103333

Figure 2.

Figure 2

Concentration response of factor (F)VIII in the thrombin generation assay (TGA) with varying trigger concentrations. Concentration response of FVIII to different triggers: (A) tissue factor (TF; 0.5-20 pM), (B) activated FXI (FXIa; 0.1-8 milliunits [mU]/mL), and (C) 1 pM TF + FXIa (0.1-8 mU/mL). The x-axis scale is logarithmic (log10). Circle markers: FVIII measurements; colored lines: fit to FVIII measurements. ETP, endogenous thrombin potential; IU, International Units; VI, velocity index.