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Effect of activated factor (F)IX (FIXa) trigger concentrations on thrombin generation. Colored markers: FVIII measurements; colored lines: fit to FVIII measurements. Concentration response of FVIII in the presence of different concentrations of FIXa. The x-axis scale is logarithmic (log10). ETP, endogenous thrombin potential; IU, International Units; Peak, thrombin peak; TGA, thrombin generation assay; VI, velocity index.
