Table 2.
LME analysis of group difference of structural gray matter in older and younger adults.
| Structural brain regions | Older adults | Younger adults | t | padj |
|---|---|---|---|---|
| Cortical thickness | ||||
| Left SFG | 2.60 (0.14) | 2.79 (0.12) | 3.98 | 0.020 |
| Left STG | 2.62 (0.13) | 2.78 (0.15) | 4.67 | 0.001 |
| Right opercular part of IFG | 2.50 (0.15) | 2.65 (0.12) | 4.02 | 0.010 |
| Right triangular part of IFG | 2.35 (0.16) | 2.51 (0.12) | 3.84 | 0.030 |
| Right rMFG | 2.28 (0.12) | 2.38 (0.09) | 4.04 | 0.010 |
| Right SFG | 2.58 (0.15) | 2.77 (0.12) | 3.85 | 0.030 |
| Right STG | 2.66 (0.14) | 2.85 (0.14) | 5.46 | 0.001 |
| Cortical surface area | ||||
| No significant group differences were observed | ||||
| Subcortical gray matter volume | ||||
| Left thalamus | 7070.37 (883.98) | 8172.44 (785.99) | 5.27 | 0.001 |
| Left putamen | 4319.68 (605.49) | 5132.17 (666.65) | 4.46 | 0.001 |
| Left nucleus accumbens | 406.11 (146.31) | 561.22 (155.52) | 4.18 | 0.010 |
| Right thalamus | 6926.69 (805.22) | 7795.00 (731.05) | 4.76 | 0.001 |
| Right putamen | 4371.69 (639.28) | 5207.18 (577.24) | 5.07 | 0.001 |
| Right nucleus accumbens | 464.09 (104.65) | 574.37 (110.38) | 4.26 | 0.010 |
SFG, superior frontal gyrus; STG, superior temporal gyrus; IFG, inferior frontal gyrus; rMFG, rostral middle frontal gyrus.