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. Author manuscript; available in PMC: 2026 Feb 17.

Published in final edited form as: Arch Toxicol. 2022 Apr 21;96(6):1865–1880. doi: 10.1007/s00204-022-03294-2

Figure 9. — μ-Opioid receptor (MOR) activation as exerted by authentic serum and urine samples. A. Patient serum (left panel) and urine (right panel). B. Zoom-in of the profiles obtained for blank serum and blank urine. The difference in baseline signal indicates the presence of a matrix effect. Results are shown as mean receptor activation ± standard deviation of one representative experiment, in which each sample was run in duplicate. Note the difference in scales of the y-axes.

Figure 9. — μ-Opioid receptor (MOR) activation as exerted by authentic serum and urine samples. A. Patient serum (left panel) and urine (right panel). B. Zoom-in of the profiles obtained for blank serum and blank urine. The difference in baseline signal indicates the presence of a matrix effect. Results are shown as mean receptor activation ± standard deviation of one representative experiment, in which each sample was run in duplicate. Note the difference in scales of the y-axes.